整合報告

Breast, labeled as "with calcification", stereotic biopsy
Breast, labeled as "without calcification", stereotic biopsy

MACROSCOPIC
1. Specimen type: stereotic biopsy
2. Specimen size:  
   A: More than ten tissue fragments
   B: More than ten tissue fragments
3. Fixation time: 6 hrs 0 mins
4. Cold ischemic time: < 1 hr

   All for sections and labeled as:                      Jar 0
 With calcification
 Without calcification

MICROSCOPIC
1. Diagnosis: 
    Invasive carcinoma of no special type 
    Invasive lobular carcinoma
    Invasive carcinoma
    Others (請自行描述)
2. Grade I (score 3-5) / Grade II (score 6,7) / Grade III (score 8,9):
     I. Tubule Formation:
     II. Nuclear Pleomorphism:
     III. Mitotic Count:           
          * Tubule formation: score 1/ 2/ 3
              Majority of tumor greater than 75% (score = 1)
              Moderate 10% to 75% (score = 2)
              Minimal less than 10% (score = 3)
          * Nuclear pleomorphism: score 1/ 2/ 3
              Small regular nuclei (score = 1)
              Moderate increase in size, etc (score = 2)
              Marked variation in size, nucleoli, chromatin clumping, etc 
              (score= 3)
          * Mitotic count: score 1/ 2/ 3
              ≤3 mitoses per mm2 (score = 1)
              4-7 mitoses per mm2 (score = 2)
              ≥8 mitoses per mm2 (score = 3)
3. Hormone studies and Her-2/neu:
   ER (SP1): positive (  %;  weak  intermediate  strong)  negative;        
   PR (1E2): positive (  %;  weak  intermediate  strong)  negative;
   Her-2/neu (4B5): 0/3+( %), 1+/3+, 2+/3+, 3+/3+
4. Ki-67 proliferative index:   % 
5. With DCIS (LCIS): Present, highlighted under p63 staining / Absent
   (1) Nuclear grade: 1 /2 /3
   (2) Architectural pattern: Comedo / Non-comedo 
   (3) Tumor necrosis: Absent / Present 
6. Comments: Nil.

Ref:

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